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The Influence of a Mobilisation of the Lesser Omentum on the Capacity of the Portal Vein, Measured with Echo-Doppler

Journal: Unpublished MSc thesis Wiener Schule für Osteopathie, Date: 2008/11, Pages: 102, type of study: controlled clinical trial

Free full text   (https://www.osteopathicresearch.org/s/orw/item/2932)

Keywords:

capacity [10]
lesser omentum [1]
mobilisation [14]
visceral osteopathy [55]
portal vein [4]
controlled clinical trial [283]
WSO [433]

Abstract:

Objective: It was the aim of this study to examine physiological changes by a visceral osteopathic intervention. In special: Does a mobilisation of the lesser omentum influence the capacity of the portal vein? Subjects and Methods: Twenty healthy male adults (age 23-40) were assigned to two equivalent groups. Groups were matched by age, body height and body weight. Inclusion criteria were a BMI ≤ 27, age 18-45 years, non-smoking and alcohol intake <25 g/day. Additional exclusion criteria were drug intake, inflammatory diseases, abdominal surgical interventions and known heart or liver pathologies. The members of the test group (mobilisation group/MT, n=10) were treated with a mobilisation technique for the lesser omentum, the members of the sham group (non-specific-technique group/NST, n=10) with a manual abdominal compression in the height of the navel in direction of the spine. Both techniques were applied for three minutes. Participants as well as examining medical specialists were blinded against the administered intervention. The measurement of the portal venous diameter and mean blood flow velocity in the portal vein was performed at four moments. For each measurement, the capacity of the portal vein was calculated based on these data. Two trials, one initial medical examination (x1) and half an hour later another comparison measurement (x2) were performed for the assessment of the baseline. The third measurement (y) was done directly after administration of the particular intervention technique and the fourth one hour later (z). Characteristics of the portal vein were measured in decubitus position left of the subjects by means of a 3.5 MHz transducer with colour-coded duplex sonography. The flow velocity was measured by means of a PW-Doppler ultrasound device Toshiba Xario. Statistical software used for evaluation was R 2.7.1 and SPSS® 14.0. Master Thesis Hanno Halbeisen, Donau Universität Krems IV Results: The results of the two baseline measurements (x1, x2) of the portal vein capacity as well as the test-to-test variability in the NST group and MT group were comparable. In contrast, heart rate, blood pressure, the diameter of the portal vein and the blood flow velocity were not stable but might indicate relaxation effects. The results of the baseline measurement of the parameters capacity, diameter and flow velocity are assorting well with literature data. After the interventions (measurement y) capacities increased by approximately 1.3 ml/min/kg body weight could be observed (MT group: mean (standard deviation): 11.3 (4.0) ml/min/kg, NST group: 11.5 (6.2) ml/min/kg). The increase in capacity is not significant in either group, but slightly more distinct in the MT group, due to the lower base data (MT group: p=0.10, NST group: p=0.33). These group differences in the change in capacity are not significant, either (ANOVA: p=0.97). One hour after the intervention (measurement z), a mean flow of 10.0 (3.4) ml/min/kg body weight could be observed in the MT group and of 9.6 (2.6) ml/min/kg in the NST group. In both groups the base level was re-established. Conclusion: The current data show, that there is no significant difference in the effects on the capacity of the portal vein between the specific visceral mobilisation technique for the lesser omentum and a non-specific technique with a manual abdominal compression in the height of the navel in direction of the spine. The validity of these results above all is restricted by the low number of participants (10 per group).


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