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Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

Journal: The AAO Journal Date: 2022/06, 32(2):Pages: 31. doi: Subito , type of study: randomized controlled trial

Free full text   (https://meridian.allenpress.com/aaoj/article/32/2/15/482674/LBORC-NUFA-Poster-Abstracts-2022-Students)

Keywords:

anosmia [3]
olfactory dysfunction [1]
COVID-19 [76]
OMT [2951]
osteopathic manipulative treatment [2973]
randomized controlled trial [710]

Abstract:

Introduction: In 2019, the emergence of SARS-CoV2 created countless unique threats to public health. One of the cardinal symptoms is the loss of smell. Most people regain their sense of smell; however, some maintain decreased, absent, or abnormal olfaction long after the infection has resolved, leading to increased safety concerns and decreased quality of life. Objective: This 2021 study represents a single-blinded pilot trial to examine the effects of a single Osteopathic Manipulative Therapy (OMT) treatment on individuals with self-identified prolonged post-COVID anosmia, hyposmia or parosmia (n=20).It was hypothesized that the OMT group would have a greater improvement in olfactory function when compared to the placebo group. Methods: Participants were randomly assigned to the OMT group or a placebo/light touch/sham group and subsequently underwent pre-intervention smell testing of four items (orange, red onion, bourbon, and perfume). Next, each group underwent assigned intervention followed by post-intervention smell testing to determine change in olfactory function. Results: A Mann-Whitney test indicated that the post and pre-intervention differences in the correct smell intensity scores of red onions were significantly higher for participants who received OMT treatment (Mdn = 2.00) compared to participants in the placebo group (Mdn=1.00), U=20, p=0.19, r=5. There was a correlation of an increase in smell intensity in 2 out of the 3 remaining smell items, and the mean difference between presmell treatment and post-smell treatment in the OMT group was higher than the placebo group. Conclusion: While the sample size was small and the method of smell assessment could be improved, this OMT protocol, and potentially others, should be investigated further as a promising potential treatment for prolonged post-COVID olfactory dysfunction.


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