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Efficacy of a standardized osteopathic manipulative therapy protocol on pulmonary function and symptomatology in moderate persistent asthmatic children

Journal: Annals of Allergy, Asthma and Immunology Date: 2010/11, 105(5):Pages: A36‐A37, type of study: randomized controlled trial

Full text    (https://www.annallergy.org/issue/S1081-1206(10)X0012-6)

Keywords:

allergic asthma [2]
asthma [42]
child [312]
children [228]
college [44]
immunology [3]
lung function [13]
osteopathic manipulative treatment [2973]
OMT [2951]
conference abstract [108]
randomized controlled trial [710]

Abstract:

Introduction: Asthma is a common respiratory disease process in children. Osteopathic manipulative therapy (OMT) includes manipulation of the musculoskeletal and lymphatic systems. We developed a study to determine if osteopathic therapy would have an effect on children with asthma. Methods: Children 4 to 17 years old with moderate persistent asthma were eligible and block randomized to two groups. Approval was obtained from University Hospitals, Cleveland. Results: The treatment group showed no improvement in FEV1 with a change of 0.001L, while the control FEV1 decreased by 0.075L. Analysis showed no significant improvement in FEV1 in either the treatment (p=0.982) or the controls (p=0.081). Analysis of the change in FEF25‐75, showed no improvement in either the treatment (p=0.532) or the controls (p=0.401). Comparing subjective scores, there was a nonsignificant improvement in the treatment group (p=0.331), but no improvement in symptom score with the controls. Discussion: Our findings showed no significant difference between the treatment and control groups. The increase in FEV1 in the treatment group of 0.001L is not clinically significant. The control group average FEV1 decreased by 0.075L. While clinically measurable, it did not meet statistical significance. Similar results were seen in FEF25‐75, with an increase in the treatment group of 0.069L and a more impressive but not statistically significant increase of 0.442L in the controls. The subjective asthma symptoms showed no difference between treatment and control groups. The treatment group had an average starting score of 4.83 with improvement to 4.9 (p=0.331). The control group had the same average pre and post treatment score of 4.9. There are limitations that may have affected the results. Primarily, the study was limited in size. Another limitation was the study was not double blinded. The treating physician was aware of which patient was receiving targeted treatment versus those in the control group. Finally, the measurements of symptomatology and FEV1 were patient dependent. Conclusions: A specific OMT protocol did not significantly improve pulmonary function or subjective asthma symptoms, in pediatric patients with moderate persistent asthma. Further studies would be warranted in this field.


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