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CV4 technique as a tool to decrease psychological stress in osteopathic medical students

Journal: The Journal of the American Osteopathic Association Date: 2005/07, 105(7):Pages: 330. doi: Subito , type of study: controlled clinical trial

Full text    (https://www.degruyter.com/document/doi/10.7556/jaoa.2005.105.7.317/html)

Keywords:

controlled clinical trial [316]
cranio-sacral osteopathy [223]
CV4 technique [14]
medical students [647]
osteopathic medicine [2025]
stress [110]
USA [1656]

Abstract:

Stressors produce imbalance of the body homeostasis and evoke adaptive responses through the HPA axis. Medical students are confronted every day with major challenges during their training years, making them very susceptible to stress. Stress becomes maximal at examination periods. Hypothesis: Our student population is under psychological stress which can be reduced by a particular manipulative technique, CV-4, and the effect is measurable by using the appropriate circulating biomarkers. Study design: Subjects were 33 volunteer OMS I and II. Subjects were studied in 3 different periods: 1. Nonstress period (baseline). 2. Stress period. 3. Stress + intervention. Intervention consisted on 8 consecutive days when CV-4 was administered. Students were divided into a CV4 treatment group and a sham group. The sham treatment consisted in cradling the head for 15 minutes. The response variables studied were: WBC count, C-reactive protein, ACTH, cortisol, epinephrine. Methods: CRP, ACTH, cortisol and epinephrine were measured by ELISA Results. WBC showed an increase under stress conditions and a significant decrease after intervention. CRP showed a decrease under stress conditions with a tendency to go back to the original values with the intervention. Stress hormones were not significantly elevated in our subject population between non-stress and stress conditions and show little variations with CV4. Conclusions: The results from our study suggest that punctual measurements of stress hormones have limited value to assess stress in a human population. Inter and intra individual confounding factors mask the variation due to stress. Moreover, our student population suffers from chronic stress with very little response from baseline to stress periods. However, our data also suggest that WBC count and CRP could better reflect the beneficial effects from CV4. Furthermore, our data demonstrates that the study is feasible, our model of psychological stress is appropriate to test our hypothesis. Urinary 17-corticosteroids and 24 h urinary cortisol might prove to be better indicators of overall hormonal changes in stress and can be used in future studies.


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