Advanced search

Search results      


Retrospective Study of Osteopathic Manipulative Treatment Use for Pain in Patients with Ehlers Danlos Syndromes and Hypermobility Spectrum Disorder (EDS/HSD)

Journal: Journal of Osteopathic Medicine Date: 2023/12, 123(12):Pages: A146-A147. doi: Subito , type of study: retrospective study

Full text    (https://www.degruyter.com/document/doi/10.1515/jom-2023-2000/html)

Keywords:

Ehlers-Danlos syndrome [3]
hypermobility spectrum disorder [1]
OMT [2951]
osteopathic manipulative treatment [2973]
retrospective study [213]

Abstract:

Statement of Significance: EDS/HSD are a diverse group of connective tissue disorders that are generally characterized by joint hypermobility, skin hyper-extensibility, and poor wound healing. 1, 2 Most EDS/HSD patients experience varying musculoskeletal pain in terms of location, intensity, and frequency. 2, 3 The pain includes arthralgia, neuralgia, headaches, and visceral pain.4 While there are treatment options like painkillers, physical therapy, and surgery, their long-term effectiveness lacks clear evidence. Novel pain-reduction interventions for patients with EDS/HSD are much needed.4 Previous case reports suggested that applying Osteopathic Manipulative Treatment (OMT) was safe and improved pain and/or function in patients with EDS/HSD. However, the use of OMT to care for patients with EDS/ HSD has not been well-investigated. Therefore, the aim of this retrospective study is to determine if OMT provided during patient care significantly improved pain from EDS/HSD patients. Research Methods: A retrospective cohort study, approved by NYIT-IRB (BHS1565), was performed on patient charts in the EDS and HSD Treatment Center at the outpatient Academic Health Care Center from 2015 to the present. The data from de-identified patients with EDS/HSD were then analyzed. Patients 10-73 years old were selected by ICD-9/10 codes for hypermobile EDS (hEDS), vascular EDS (vEDS), classical EDS (cEDS), HSD, join hypermobility syndrome (JHS), and Hypermobility and CPT codes for OMT. Patients were excluded if they had autoimmunity, neurodegeneration, and/or cancer present. The no-OMM group included physical, occupational, or psychological therapy. A qualitative assessment of pain was used to determine if pain had improved after treatment. Data Analysis: Preliminary data have been collected from the total of 154 de-identified patients with EDS/HSD. The mean age for patients was 37 (±13.6; n=154) years old. They were 94% (145) female; 6% (9) male. Joint hypermobility was present in 99% while 4% (6) had vascular EDS. There was a strong positive correlation (r=0.0143) of arthralgias and myalgias with age among those with a Beighton Score of at least 4. Genetic testing was performed for 27% (42), and 30% (8) of those tested had a genetic variant linked to connective tissue. The most commonly used genetic test was GeneDx Heritable Disorders of Connective Tissue Panel tissue-sequencing and del/dup panel. At least 92% (142) of the patients presented with pain at their initial OMT visit. Analgesics or herbs were concurrently taken by 10% (15) of the patients. Although 54% (83) patients had OMT, 5% (4) had trigger-point and/or prolotherapy injections with OMT. 30% (25) of the patients had other rehabilitative therapies without OMT, and 10% (15) had a Geneticist or Family Practice consult only. The mean number of regions treated with OMT was 4 (±2; ranged 1-8). Cranial (63.0%) and myofascial release (63.0%) were the most frequently provided OMT techniques. There was a significant improvement of pain after OMT in approximately 74% (114) of the patients. Conclusion: The preliminary analysis from the extensive retrospective chart review of the patients with EDS/HSD confirmed that most patients reported some levels of pain. Of those with joint hypermobility, pain in the joints and muscles increased with age. The results of this initial chart review suggested that most patients in the EDS and HSD Center who underwent OMT treatment reported improvement in their initial assessment of pain. Further analysis also demonstrated a significant improvement of the pain after OMT treatment. However, the extent of the effects or long-term effects of OMT on the pain management remains unclear. Therefore, future prospective studies of OMT in the treatment of pain in individuals with EDS/HSD are necessary to determine the best osteopathic approach.


Search results      

 
 
 






  • ImpressumLegal noticeDatenschutz


ostlib.de/data_ypmrjasnvtbdzkuxeqcg



Supported by

OSTLIB recommends