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Effects of 7-Technique Osteopathic Manipulative Protocol on Patients With COPD

Journal: The Journal of the American Osteopathic Association Date: 2014/01, 114(1):Pages: e19. doi: Subito , type of study: randomized controlled trial

Full text    (https://www.degruyter.com/document/doi/10.7556/jom_2014_01.0001/html)

Keywords:

chronic obstructive pulmonary disease [31]
COPD [40]
OMT [3779]
osteopathic manipulative treatment [3799]
pilot study [196]
randomized controlled trial [899]

Abstract:

Introduction: There have been few studies that have measured the long-term effect of osteopathic manipulative treatment (OMT) on chronic obstructive pulmonary disease (COPD). Hypothesis: This pilot study tested the hypothesis that an OMT intervention protocol used over a series of visits would be safe, feasible and would improve pulmonary function in clinically diagnosed COPD patients. Methods: This randomized, single-blinded pilot study was completed over 18 months with 2 recruitment cycles including 25 participants older than 40 years. The first cycle consisted of 7 participants with 4 in the OMT group and 3 in the sham group. The second cycle consisted of 18 participants with 8 in the OMT group and 10 in the sham group. OMT consisted of 7 standardized techniques. The sham group received light touch protocol. Both protocols occurred over 4 visits. Objective measures obtained included pulmonary function testing (PFT) and a 6-minute walk test (6MWT). Subjective measures obtained were the Clinical COPD Questionnaire (CCQ) and St George's Respiratory Questionnaire (SGRQ). Results: A difference was noted between sham and OMT groups forced expiratory flow (FEF) 25%-75%, across 4 visits. We did find a trend of improvement in both groups at baseline visit post-FEF compared to subsequent visits. Baseline (z=−.575, P=.572), visit 1 (z=−.767, P=.467), visit 2 (z=−.1.230, P=.235), visit 3 (z=−1.830, P=.072). However, when treatment and sham groups were collapsed and baseline posttest FEF was compared to visit 3 posttest FEF, a significant improvement was noted, (z=2.251, P=.024). The 6-minute walk test also demonstrated a significant difference when the groups were collapsed (z=−2.617, P=.009). There were no major adverse events during the duration of the study and the study protocol proved feasible to implement. Conclusion: These pilot results demonstrate the possible benefit of OMT on certain pulmonary function parameters, specifically with improvements in FEF and physical exertion as demonstrated by the 6MWT in patients with COPD. Pilot results are promising and should be replicated with a larger sample size. The intervention was safe and well tolerated without need for design modifications.


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