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Effects of Osteopathic Manipulative Treatment on Symptom Severity and Functional Status in Carpal Tunnel Syndrome

Journal: The Journal of the American Osteopathic Association Date: 2004/08, 104(8):Pages: 338. doi: Subito , type of study: randomized controlled trial

Full text    (https://www.degruyter.com/document/doi/10.7556/jaoa.2004.104.8.337/html)

Keywords:

carpal tunnel syndrome [27]
OMT [3102]
osteopathic manipulative treatment [3124]
randomized controlled trial [766]
wrist [12]

Abstract:

Objective: Carpal tunnel syndrome (CTS), caused by compression of the median nerve within the carpal canal, affects up to 10% of the adult population in the United States with medical costs exceeding $2 billion annually. Complaints include pain and restricted movement of the wrist and hand. The goal of this prospective, randomized, blinded clinical trial is to evaluate the benefits of Osteopathic Manipulative Treatment (OMT) on the symptom severity and daily functioning of subjects with CTS. Methods: A power analysis indicated that 25 individuals in each of two groups, an OMT and a placebo control group (sub-therapeutic ultrasound) would be adequate. Eligibility criteria include individuals between 21 and 70 with a clinical diagnosis of CTS and specific nerve conduction values that validated the presence of nerve impingement. Primary outcome measures for this study are symptom severity and functional status scores, with secondary outcomes of strength measures. Subjects receive six treatments with measures taken prior to beginning treatment, prior to the fourth treatment, and one week following the last treatment. Results: Twenty-one subjects have completed the study to date. Preliminary analysis, using paireed T-test, shows a significant difference between pre and post treatment measures for the symptom severity (p=0.003) and functional status scores (p=0.017) in the OMT group and are not significant in the sham ultrasound group. Strength findings were mixed due to further division of groups to account for gender differences in strength. Conclusions: Trends based on initial analysis are positive. Subjects will be recruited through June, 2004 with a goal N = 50. Final data analysis will include ANOVA with repeated measures and analysis of strength measures.


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